For a step back from the beer and nightlife, try a pensive morning spent in Prague's Jewish Quarter. I had a few reservations about the entry fee (the equivalent of $21 for the cemetery and all synagogues except the Old-New), but ended up spending a solid 5 hours walking around, reading the informational plaques and pondering almost every single display in the museums. And I'm not a big history buff or museum advocate! But I learned a LOT about Jewish life, and ended up understanding a book I read after my trip a lot better because it alluded to a lot about Jewish traditions/rituals I otherwise would not have understood. If you're Jewish, I think you'll appreciate this cultural and historical tour even more - I'm not Jewish and I thoroughly enjoyed it.