Hotels in Lake City
Enter your dates for the latest hotel rates and availability.
Scroll down to see hotels
Filter by:
Hotel Star Rating
≤2345
Guest Rating
Amazing 9+Great 8+Good 7+Pleasant 6+Popular filters for Lake City
Breakfast includedHotel1 king bedVery Good 8+PoolPets welcomeFairfield by MarriottSpaPay at HotelFamily roomProperty Type
HotelMotelProperty facilities & services
PoolPets welcomeCurrency exchangeElevatorSpa24-hour front deskGymWi-Fi in public areasParking availableFree parkingSmoking areaConference roomGolf courseWake-up callLuggage storageBarbecueRestaurantEV charging stationBarWe found 24 hotels for you in Lake City
Trip.com offers top-picked hotels in Lake City, including reviews, price estimates, and facility details to help you choose the best option for you.
Most Booked
Lowest price
Closest to downtown
Highest Rated
49
Very Good
103 reviews
8.3/10
1 night
From NZD 115
63
Hotels in Lake City
"The room was clean, the bed was very comfortable, the environment was beautiful, the free breakfast was normal, the service was thoughtful, the attitude was warm, and the facilities were complete."
Great
105 reviews
9.3/10
1 night
From NZD 205
95
Great
98 reviews
9.2/10
1 night
From NZD 181
59
Hotels in Lake City
Experience Lake City's newest Marriott Hotel, located beside Lake City Medical Center, close to I-75 & I-10. Centrally located to Gainesville, Jacksonville, and Tallahassee. Feel the many charms of our historic downtown, numerous restaurants and even discover the many wonders of our gorgeous natural springs. TownePlace Suites by Marriott is an extended-stay hotel where you can balance work and life as you like, with the comfort, flexibility and affordability you require. Relax and feel at home with a fully equipped kitchen and high-speed Internet access. PET FRIENDLY!
Amazing
49 reviews
9.6/10
1 night
From NZD 230
71
Hotels in Lake City
"The hotel is in a good spot very convenient didn't like the fact that the room did not have a shower curtain and the room also had roaches and the pet fee was expensive other than that the hotel site looks nice"
98 reviews
5.5/10
1 night
From NZD 98
79
Amazing
98 reviews
9.4/10
1 night
From NZD 214
59
Very Good
76 reviews
8.8/10
1 night
From NZD 195
60
Hotels in Lake City
"Best place. Great people, locations and awesome breakfast. Tammy is exceptional from breakfast. Just a pleasure being at this hotel. They understand hospitality."
Very Good
106 reviews
8.8/10
1 night
From NZD 166
86
Hotels in Lake City
"該酒店位於10和公路邊上，方便過路客在此打尖休息一下。但酒店的旁邊緊鄰的似乎是一個大貨車停車場（庫），那裡的貨櫃裝有空調器夜間一直在運行工作。我住的房間剛好面向這些設備，所以夜間明顯感覺室內受到外部設備運行噪音的干擾。這對於睡眠環境要求稍有苛刻的住客就需要考慮考慮選擇該酒店面向高速公路的一側的房間或乾脆換其它家酒店，以規避噪音對於睡眠質量的影響。我本次入駐的實際感受希望對於有需要的旅客有參考價值。"
101 reviews
7.0/10
1 night
From NZD 99
86
Hotels in Lake City
"Tappa intermedia di un Road trip, hotel nuovissimo, pulito e con letto comodo, quello che avevo bisogno dopo 6 ore di autostrada"
Amazing
76 reviews
9.4/10
1 night
From NZD 221
Trip.com's insights for hotels in Lake City
Plan smarter with Trip.com’s data-backed insights on travel seasons so that you can book your Lake City hotel at the right time!
Which month offers the lowest hotel rates in Lake City?
May is the most affordable month to book a hotel in Lake City, with average nightly rates around NZD 136. Prices peak in March, when rates reach about NZD 275 per night.
(Based on Trip.com data from June 16, 2025 to June 16, 2026.)
(Based on Trip.com data from June 16, 2025 to June 16, 2026.)
0
NZD 100
NZD 200
NZD 300
NZD 233
Jun
NZD 146
Jul
NZD 183
Aug
NZD 184
Sep
NZD 162
Oct
NZD 188
Nov
NZD 272
Dec
NZD 169
Jan
NZD 208
Feb
NZD 275
Mar
NZD 149
Apr
NZD 136
May
What is the cheapest day of the week for hotels in Lake City?
Hotel rates in Lake City are typically lowest on Saturday, with average nightly rates around NZD 164. Wednesday tends to be the most expensive, averaging NZD 218 per night.
(Based on Trip.com data from June 16, 2025 to June 16, 2026.)
(Based on Trip.com data from June 16, 2025 to June 16, 2026.)
0
NZD 100
NZD 200
NZD 300
NZD 178
Mon
NZD 165
Tue
NZD 218
Wed
NZD 190
Thu
NZD 169
Fri
NZD 164
Sat
NZD 187
Sun
Explore accommodation types in Lake City
Immerse yourself in the vibrant atmosphere of Lake City with our handpicked accommodation options
Top hotel picks in Lake City
See all
Check out these top-booked hotels from the past 30 days!
5.7/10
90 reviewsKnights Inn Lake City
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
Knights Inn Lake City offers comfortable beds at a convenient location off I-75 and within walking distance to several restaurants 1 mile away from Lake City Mall 20 miles from O Leno State Park and near various beautiful natural springs. Complimentary coffee and WiFi all rooms include microwave mini-fridge flat-screen TV with cable channels and desk with ergonomic chair. We are pet friendly fees and restrictions apply.
Select dates to view prices
8.5/10
102 reviewsLa Quinta by Wyndham Lake City
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
For a memorable stay in the Gateway to Florida join us at La Quinta Inn and Suites by Wyndham Lake City off I-75 and I-10 and within driving distance of Gainesville Regional Airport GNV. Close to many businesses and restaurants we are steps from Lake City Medical Center and two miles from youth tournaments in Southside Sports Complex. Gainesville home to the University of Florida is 45 miles south while Jacksonville is 64 miles east. Enjoy nearby Ichetucknee Springs State Park and then find comfort in our pool gym and free WiFi.
Select dates to view prices
8.0/10
99 reviewsQuality Inn Lake City
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
Located in Lake City, Quality Inn Lake City is within a 15-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center. This hotel is 0.8 mi (1.2 km) from Regal UA Cinema 90 and 1 mi (1.6 km) from Lake City Mall.
Be sure to enjoy recreational amenities including an outdoor pool and a fitness center. This hotel also features complimentary wireless internet access, a fireplace in the lobby, and a picnic area.
A complimentary self-serve breakfast is served daily from 6 AM to 9:00 AM.
Featured amenities include a business center, a 24-hour front desk, and an elevator. Free self parking is available onsite.
Make yourself at home in one of the 55 guestrooms featuring refrigerators and LCD televisions. Your room comes with a pillowtop bed. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations with rainfall showerheads and hair dryers.
Select dates to view prices
7.5/10
101 reviewsDays Inn by Wyndham Lake City I-75
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
Welcome to the Days Inn Lake City FL.
Whether you are traveling for business or pleasure you will appreciate a hotel that offers useful amenities and superior customer service. This is exactly what you will find at our two diamond Days Inn hotel. We are conveniently located off I-75 exit 427 .25 miles from 1-75 the closest Days Inn to Lake City VA hospital and just four miles west of Historic Downtown Lake City. You will find plenty of activities for everyone in your family to enjoy whether you are exploring historic Olustee Battlefield Enjoying nature in the Osceola National Forest or picnicking at the Itchetucknee State Park or the Suwanee River. Enjoy free continental breakfast together with coffee tea and juice and stay connected with free Wifi.
Select dates to view prices
8.4/10
100 reviewsRegal Inn
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
With a stay at Regal Inn in Lake City, you'll be a 5-minute walk from Regal UA Cinema 90 and 10 minutes by foot from Lake City Mall. This hotel is 0.6 mi (0.9 km) from Fresenius Medical Care at Lake City Medical Center and 0.6 mi (1 km) from Lake City Medical Center.
This hotel offers designated smoking areas.
Free self parking is available onsite.
Make yourself at home in one of the 20 guestrooms. Complimentary wireless internet access is available to keep you connected. Bathrooms feature bathtubs or showers, hair dryers, and toothbrushes and toothpaste. Conveniences include a turndown service and irons/ironing boards, as well as phones with free local calls.
Select dates to view prices
7.6/10
70 reviewsMotel 6 Lake City, FL – Medical Center
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
With a stay at Motel 6 – Lake City, Fl – Medical Center in Lake City, you'll be within a 10-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center. This motel is 0.7 mi (1.1 km) from Regal UA Cinema 90 and 1 mi (1.5 km) from Lake City Mall.
This motel offers designated smoking areas.
Featured amenities include a 24-hour front desk and a vending machine. Free self parking is available onsite.
Make yourself at home in one of the air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected. Bathrooms with bathtubs or showers are provided.
Select dates to view prices
8.8/10
97 reviewsHoliday Inn & Suites LAKE CITY by IHG
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
Welcome to the only full-service hotel in Lake City, FL, where Southern hospitality and all the comforts of Holiday Inn® & Suites await. Conveniently located at the crossroads of I-10 and I-75, our Lake City, Florida, hotel is perfect for both business and leisure travelers.
Corporate guests appreciate a 24-hour Business Center, free high-speed Wi-Fi, and versatile meeting space for up to 150 attendees. Vacationers love our close proximity to area favorites like Ichetucknee Springs, Suwannee River State Park, and the Spirit of the Suwannee Music Park, plus easy access to Gainesville and the Florida Gators.
Start your morning with a made-to-order breakfast in The Atrium, wind down with dinner and drinks in the evening, or relax in our indoor heated pool and 24-hour Fitness Center. Whether you're stopping on a road trip or staying awhile, our Lake City, FL, hotel is here to make every moment comfortable. Book your stay today!
Select dates to view prices
7.8/10
98 reviewsDriftwood Inn - Lake City
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
With a stay at Driftwood Inn in Lake City, you'll be a 3-minute walk from Regal UA Cinema 90 and 6 minutes by foot from Lake City Mall. This hotel is 1 mi (1.6 km) from Fresenius Medical Care at Lake City Medical Center and 1.1 mi (1.7 km) from Lake City Medical Center.
Make use of convenient amenities, which include complimentary wireless internet access and a vending machine.
Featured amenities include a 24-hour front desk, coffee/tea in a common area, and a vending machine. Free self parking is available onsite.
Make yourself at home in one of the 20 air-conditioned rooms featuring refrigerators and LED televisions. Satellite television is provided for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include microwaves, and housekeeping is provided daily.
Select dates to view prices
6.2/10
51 reviewsGuest Inn Lake City
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
With a stay at Guest Inn in Lake City, you'll be within a 5-minute drive of Lake City Mall and Southside Sports Complex. This hotel is 2.5 mi (4 km) from Southside Recreation Complex and 3.8 mi (6.1 km) from Lake City Columbia County Historical Museum.
Make use of convenient amenities, which include complimentary wireless internet access and a vending machine.
Featured amenities include a 24-hour front desk, coffee/tea in a common area, and a vending machine. Free self parking is available onsite.
Make yourself at home in one of the 50 air-conditioned rooms featuring flat-screen televisions. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include phones, as well as laptop-compatible safes and desks.
Select dates to view prices
9.2/10
102 reviewsComfort Suites Lake City
Hotel near Lake City
Popular choice among guests booking hotels in Lake City
A stay at Comfort Suites Lake City places you in the heart of Lake City, within a 15-minute walk of Fresenius Medical Care at Lake City Medical Center and Lake City Medical Center. This hotel is 0.9 mi (1.5 km) from Regal UA Cinema 90 and 1.1 mi (1.7 km) from Lake Shore Primary Care West.
Don't miss out on recreational opportunities including an outdoor pool and a fitness center. This hotel also features complimentary wireless internet access, gift shops/newsstands, and a television in a common area.
A complimentary buffet breakfast is served daily from 6:00 AM to 9:00 AM.
Featured amenities include complimentary wired internet access, a 24-hour business center, and a 24-hour front desk. Free self parking is available onsite.
Make yourself at home in one of the 94 guestrooms featuring refrigerators and flat-screen televisions. Your room comes with a pillowtop bed. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Bathrooms have shower/tub combinations and hair dryers.
Select dates to view prices
FAQs About Hotels in Lake City
What popular hotels in Lake City have parking?
If you're planning on driving to Lake City, why not stay at
Americas Best Value Inn Lake City,Comfort Suites Lake CityandHome2 Suites by Hilton Lake City
? These are all popular hotels with parking lots.
At which popular hotels in Lake City can I try local foods?
Those who like trying local foods might want to consider staying at
Days Inn by Wyndham Lake City I-75,Howard Johnson by Wyndham Lake CityandHoliday Inn & Suites LAKE CITY by IHG
. There are lots of famous restaurants serving local dishes near these hotels.
When travelling to Lake City, which hotels have pools?
Summer is a great season to take your kids or family on a trip to Lake City.
Best Western Plus Lake City,Comfort Suites Lake CityandHoward Johnson by Wyndham Lake City
are popular hotels with pools.
Of all the hotels in Lake City, which hotels have the highest user ratings?
When travelling to Lake City for the first time, many travellers find it difficult to choose a hotel to stay in. According to Trip.com data,
Best Western Plus Lake City, Home2 Suites by Hilton Lake City and Americas Best Value Inn Lake City
are popular hotels with high ratings, making them good choices for your trip.
At what hotels in Lake City can I try local breakfast foods?
A delicious breakfast is a great way to kick start your day. At
Days Inn by Wyndham Lake City I-10,Fairfield Inn & Suites Lake CityandBaymont by Wyndham Lake City
, guests can enjoy Lake City-style breakfasts.
What popular hotels have non-smoking rooms in Lake City?
Many guests care about the quality of the rooms they stay in and want to ensure that their rooms have fresh, clean air.
Hampton Inn & Suites Lake City,Home2 Suites by Hilton Lake CityandDays Inn by Wyndham Lake City I-10
are all popular hotels in Lake City with non-smoking rooms.
In Lake City, what popular hotels have free Wi-Fi?
When staying at a hotel, Internet access is important for both vacationers and business travellers.
Days Inn by Wyndham Lake City I-10, Best Western Plus Lake City and Americas Best Value Inn Lake City
are all popular hotels in Lake City with free Wi-Fi.
What are the most popular hotels in Lake City?
Whether you're travelling for business or going on holiday, there are many popular hotels to choose from in Lake City.
Fairfield Inn & Suites Lake City, Holiday Inn & Suites LAKE CITY by IHG and Comfort Suites Lake City
are all popular hotels to stay at.
What are some popular discounted hotels in Lake City?
There are many popular hotels in Lake City. You can find information on discounts and deals here: Trip.com Deals and Promo Codes.
In Lake City, which popular hotels have gyms?
Based on Trip.com user ratings,
Hampton Inn & Suites Lake City,Best Western Plus Lake CityandFairfield Inn & Suites Lake City
are highly rated hotels with gyms.
Lake City Hotels Information
Number of reviews
2,087
Total properties
24
Weekday Avg. Price
NZD 208
Weekend Avg. Price
NZD 254
Trending hotel
Knights Inn Lake City