App
Customer Support
EUR
Find Bookings
Trip.com
>
Cheap Flights
>
Bolivia
>
Santa Cruz
>
Flights from Santiago to Santa Cruz
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from Santiago to Santa Cruz Starting at €131

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • Cheapest nonstop
        SCL04:34
        3h 9m
        Nonstop
        VVI06:43
        Fri, Mar 14|Santiago - Santa Cruz|LATAM Airlines
        €135€197
        32% OFF
        32% OFF
        €197€135

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way direct flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Fri, Mar 14, arriving at Viru Viru International Airport. One-way Prices start from €135 including taxes and charges.

      • SCL04:34
        3h 8m
        Nonstop
        VVI07:42
        Wed, Apr 9|Santiago - Santa Cruz|LATAM Airlines
        €135€197
        32% OFF
        32% OFF
        €197€135

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way direct flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Wed, Apr 9, arriving at Viru Viru International Airport. One-way Prices start from €135 including taxes and charges.

      • SCL04:34
        3h 8m
        Nonstop
        VVI06:42
        Wed, Apr 2|Santiago - Santa Cruz|LATAM Airlines
        €139€197
        28% OFF
        28% OFF
        €197€139

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way direct flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Wed, Apr 2, arriving at Viru Viru International Airport. One-way Prices start from €139 including taxes and charges.

      • SCL04:34
        3h 9m
        Nonstop
        VVI06:43
        Fri, Mar 21|Santiago - Santa Cruz|LATAM Airlines
        €150
        €150

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way direct flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Fri, Mar 21, arriving at Viru Viru International Airport. One-way Prices start from €150 including taxes and charges.

      • SCL16:55
        11h 40m
        1 stop
        VVI04:35
        Sun, Apr 6|Santiago - Santa Cruz|LATAM Airlines
        €131
        €131

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Sun, Apr 6, arriving at Viru Viru International Airport. One-way Prices start from €131 including taxes and charges.

      • SCL20:00
        16h 35m
        1 stop
        VVI11:35
        Sat, Mar 22|Santiago - Santa Cruz|Sky Airline
        €133
        €133

        Choose Sky Airline flights from Santiago to Santa Cruz. The one-way connecting flight with Sky Airline departs from Arturo Merino Benitez Airport on Sat, Mar 22, arriving at Viru Viru International Airport. One-way Prices start from €133 including taxes and charges.

      • SCL14:55
        14h 50m
        1 stop
        VVI04:45
        Mon, Mar 10|Santiago - Santa Cruz|LATAM Airlines
        €135
        €135

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Mon, Mar 10, arriving at Viru Viru International Airport. One-way Prices start from €135 including taxes and charges.

      • SCL14:30
        15h 5m
        1 stop
        VVI04:35
        Mon, Mar 31|Santiago - Santa Cruz|LATAM Airlines
        €139
        €139

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Mon, Mar 31, arriving at Viru Viru International Airport. One-way Prices start from €139 including taxes and charges.

      • SCL20:50
        8h 55m
        1 stop
        VVI04:45
        Wed, Mar 19|Santiago - Santa Cruz|LATAM Airlines
        €150
        €150

        Choose LATAM Airlines flights from Santiago to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Arturo Merino Benitez Airport on Wed, Mar 19, arriving at Viru Viru International Airport. One-way Prices start from €150 including taxes and charges.

      • SCL20:00
        16h 35m
        1 stop
        VVI11:35
        Mon, Mar 10|Santiago - Santa Cruz|Sky Airline
        €150
        €150

        Choose Sky Airline flights from Santiago to Santa Cruz. The one-way connecting flight with Sky Airline departs from Arturo Merino Benitez Airport on Mon, Mar 10, arriving at Viru Viru International Airport. One-way Prices start from €150 including taxes and charges.

      • SCL01:00 pm
        3h 5m
        Nonstop
        SRZ02:00 pm
        Sat, Feb 22|Santiago - Santa Cruz|LATAM Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Santiago to Santa Cruz flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. LA864

    LATAM Airlines

    04:34

    SCL

    3.1h

    Nonstop

    07:42

    VVI

    ----T--
    Search

  2. LA890

    LATAM Airlines

    05:29

    SCL

    5.0h

    Nonstop

    09:31

    VVI

    --T--FS
    Search

  3. AR1281

    Aerolineas Argentinas

    08:55

    SCL

    2.1h

    11:00

    AEP

    SMTWT-S
    Search

  4. AR1368

    Aerolineas Argentinas

    23:05

    AEP

    3.1h

    01:10

    VVI

    S---T--

  5. AR1153

    Aerolineas Argentinas

    08:55

    SCL

    2.1h

    11:00

    AEP

    -----F-
    Search

  6. AR1368

    Aerolineas Argentinas

    23:05

    AEP

    3.1h

    01:10

    VVI

    S---T--

  7. LA640

    LATAM Airlines

    13:40

    SCL

    3.8h

    15:30

    LIM

    SMTWTFS
    Search

  8. LA2406

    LATAM Airlines

    01:00

    LIM

    2.6h

    04:35

    VVI

    SMTW-FS

  9. LA520

    LATAM Airlines

    14:55

    SCL

    3.8h

    16:45

    LIM

    SMTWTFS
    Search

  10. LA2406

    LATAM Airlines

    01:00

    LIM

    2.6h

    04:35

    VVI

    SMTW-FS

  11. AR1151

    Aerolineas Argentinas

    17:55

    SCL

    2.1h

    20:00

    AEP

    S----F-
    Search

  12. AR1368

    Aerolineas Argentinas

    23:05

    AEP

    3.1h

    01:10

    VVI

    S---T--

  13. LA2696

    LATAM Airlines

    18:00

    SCL

    3.8h

    19:45

    LIM

    SMTWTFS
    Search

  14. LA2406

    LATAM Airlines

    01:00

    LIM

    2.6h

    04:35

    VVI

    SMTW-FS

  15. H2604

    Sky Airline

    20:00

    SCL

    3.8h

    23:50

    GRU

    SMTWTFS
    Search

  16. G37714

    Gol Linhas Aereas Inteligentes

    09:30

    GRU

    3.1h

    11:35

    VVI

    SMTWT-S

  17. LA2414

    LATAM Airlines

    20:35

    SCL

    3.8h

    22:25

    LIM

    SMTWTFS
    Search

  18. LA2406

    LATAM Airlines

    01:00

    LIM

    2.6h

    04:35

    VVI

    SMTW-FS
Find more flights and airlines

Find the best time to fly from Santiago to Santa Cruz

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight tickets from Santiago (SCL) to Santa Cruz (SRZ) the cheapest?

    Airlines adjust prices for flights from Santiago to Santa Cruz based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Santiago (SCL) to Santa Cruz (SRZ) cost?

    According to Trip.com's data, the lowest price is around €307.

  • How long does it take to fly from Santiago (SCL) to Santa Cruz (SRZ) and what is the distance?

    It takes around 4 hours 5 minutes to fly from Santiago (SCL) to Santa Cruz (SRZ).

  • What is the transportation method from the main airport to downtown in Santa Cruz?

    • The distance from Viru Viru International Airport to downtown is about 17 km. It takes about 30 minutes by taxi.

  • What are the most popular airlines that fly from Santiago (SCL) to Santa Cruz (SRZ)?

    Airlines with flights from Santiago (SCL) to Santa Cruz (SRZ): LATAM Airlines.

How to find a cheap flight from Santiago to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santiago to Santa Cruz. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Santiago to Santa Cruz

Cheapest nonstop flight price€131
Cheapest round-trip ticket price€284
Off-season for travelFebruary
Peak season for travelMay
Flight distance1,893.1 km
Average flight time4 hours 5 minutes
Popular airlineAerolineas Argentinas

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.