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Flights from San Francisco to Santiago
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Flights from San Francisco to Santiago Starting at NZD 545

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • SFO00:44
        18h 11m
        1 stop
        SCL23:55
        Fri, Jan 24|San Francisco - Santiago|Copa Airlines
        NZD 545NZD 822
        34% OFF
        34% OFF
        NZD 822NZD 545

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Fri, Jan 24, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 545 including taxes and charges.

      • SFO19:13
        24h
        1 stop
        SCL00:13
        Sun, Jan 26|San Francisco - Santiago|Copa Airlines
        NZD 552NZD 822
        33% OFF
        33% OFF
        NZD 822NZD 552

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Sun, Jan 26, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 552 including taxes and charges.

      • SFO01:51
        21h 48m
        1 stop
        SCL03:39
        Mon, Mar 17|San Francisco - Santiago|Copa Airlines
        NZD 560NZD 822
        32% OFF
        32% OFF
        NZD 822NZD 560

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Mon, Mar 17, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 560 including taxes and charges.

      • SFO12:00
        14h 49m
        1 stop
        SCL07:49
        Wed, Feb 5|San Francisco - Santiago|American Airlines
        NZD 562
        NZD 562

        Choose American Airlines flights from San Francisco to Santiago. The one-way connecting flight with American Airlines departs from San Francisco International Airport on Wed, Feb 5, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 562 including taxes and charges.

      • SFO00:44
        14h 35m
        1 stop
        SCL20:19
        Sat, Jan 25|San Francisco - Santiago|Copa Airlines
        NZD 578
        NZD 578

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Sat, Jan 25, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 578 including taxes and charges.

      • SFO06:00
        20h 49m
        1 stop
        SCL07:49
        Mon, Feb 10|San Francisco - Santiago|American Airlines
        NZD 580
        NZD 580

        Choose American Airlines flights from San Francisco to Santiago. The one-way connecting flight with American Airlines departs from San Francisco International Airport on Mon, Feb 10, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 580 including taxes and charges.

      • SFO01:40
        18h 31m
        1 stop
        SCL00:11
        Thu, Apr 3|San Francisco - Santiago|Copa Airlines
        NZD 582
        NZD 582

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Thu, Apr 3, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 582 including taxes and charges.

      • SFO01:40
        18h 4m
        1 stop
        SCL23:44
        Tue, Apr 1|San Francisco - Santiago|Copa Airlines
        NZD 584
        NZD 584

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Tue, Apr 1, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 584 including taxes and charges.

      • SFO00:44
        18h 11m
        1 stop
        SCL23:55
        Wed, Jan 29|San Francisco - Santiago|Copa Airlines
        NZD 585
        NZD 585

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Wed, Jan 29, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 585 including taxes and charges.

      • SFO20:20
        19h 59m
        1 stop
        SCL20:19
        Tue, Mar 25|San Francisco - Santiago|Copa Airlines
        NZD 588
        NZD 588

        Choose Copa Airlines flights from San Francisco to Santiago. The one-way connecting flight with Copa Airlines departs from San Francisco International Airport on Tue, Mar 25, arriving at Arturo Merino Benitez Airport. One-way Prices start from NZD 588 including taxes and charges.

      • SFO01:00 pm
        3h 5m
        Nonstop
        SCL02:00 pm
        Fri, Jan 31|San Francisco - Santiago|Copa Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

San Francisco to Santiago flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. CM383

    Copa Airlines

    01:40

    SFO

    7.0h

    10:41

    PTY

    SMTWTFS
    Search

  2. CM171

    Copa Airlines

    15:35

    PTY

    6.6h

    23:11

    SCL

    SMTWTFS

  3. CM383

    Copa Airlines

    01:40

    SFO

    7.0h

    10:41

    PTY

    SMTWTFS
    Search

  4. CM497

    Copa Airlines

    15:08

    PTY

    6.6h

    22:44

    SCL

    SMTWTFS

  5. CM383

    Copa Airlines

    01:40

    SFO

    7.0h

    10:41

    PTY

    SMTWTFS
    Search

  6. CM395

    Copa Airlines

    11:48

    PTY

    6.6h

    19:24

    SCL

    SMTWTFS

  7. AA1198

    American Airlines

    06:00

    SFO

    3.5h

    11:32

    DFW

    SMTWTFS
    Search

  8. AA945

    American Airlines

    19:25

    DFW

    9.4h

    07:49

    SCL

    SMTWTFS

  9. AA3259

    American Airlines

    06:45

    SFO

    1.5h

    08:16

    LAX

    SMTWTFS
    Search

  10. AA1672

    American Airlines

    11:39

    LAX

    3.1h

    16:46

    DFW

    SMTWTFS

  11. AA945

    American Airlines

    19:25

    DFW

    9.4h

    07:49

    SCL

    SMTWTFS

  12. AA3197

    American Airlines

    07:05

    SFO

    3.5h

    12:35

    DFW

    S--WT-S
    Search

  13. AA945

    American Airlines

    19:25

    DFW

    9.4h

    07:49

    SCL

    SMTWTFS

  14. AA6411

    American Airlines

    10:11

    SFO

    1.6h

    11:44

    LAX

    SMTWTFS
    Search

  15. AA1659

    American Airlines

    14:50

    LAX

    3.1h

    19:55

    DFW

    SMTWTFS

  16. AA945

    American Airlines

    19:25

    DFW

    9.4h

    07:49

    SCL

    SMTWTFS

  17. AA1588

    American Airlines

    12:00

    SFO

    3.5h

    17:30

    DFW

    SMTWTFS
    Search

  18. AA945

    American Airlines

    19:25

    DFW

    9.4h

    07:49

    SCL

    SMTWTFS

  19. AV563

    avianca

    14:20

    SFO

    5.5h

    20:50

    SAL

    SMTWTFS
    Search

  20. AV429

    avianca

    22:10

    SAL

    4.3h

    03:25

    LIM

    --TWTFS

  21. H2803

    Sky Airline

    09:00

    LIM

    3.8h

    13:45

    SCL

    SMTWTFS

  22. AV563

    avianca

    14:20

    SFO

    5.5h

    20:50

    SAL

    SMTWTFS
    Search

  23. AV365

    avianca

    22:05

    SAL

    2.8h

    01:55

    BOG

    SMTWTFS

  24. AV115

    avianca

    06:30

    BOG

    5.9h

    13:25

    SCL

    SMTWTFS
Find more flights and airlines

Find the best time to fly from San Francisco to Santiago

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Airlines Flying from San Francisco to Santiago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
American Airlines logoAmerican AirlinesUnited Airlines logoUnited AirlinesAeromexico logoAeromexico

FAQ

  • When are flight tickets from San Francisco (SFO) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from San Francisco to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from San Francisco (SFO) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around NZD 1,339.

  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 12 km. It takes about 30 minutes by taxi.

How to find a cheap flight from San Francisco to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Francisco to Santiago. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from San Francisco to Santiago

Cheapest nonstop flight priceNZD 545
Off-season for travelNovember
Peak season for travelOctober
Flight distance9,530.72 km
Popular airlineAeromexico

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