App
Customer Support
MYR
Find Bookings
Trip.com
>
Cheap Flights
>
Belgium
>
Brussels-Capital Region
>
Brussels
>
Flights from San Francisco to Brussels
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from San Francisco to Brussels Starting at MYR 1,581

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • SFO20:00
        16h 30m
        1 stop
        BRU21:30
        Sun, Apr 6|San Francisco - Brussels|Vueling Airlines
        MYR 1,581MYR 2,651
        40% OFF
        40% OFF
        MYR 2,651MYR 1,581

        Choose Vueling Airlines flights from San Francisco to Brussels. The one-way connecting flight with Vueling Airlines departs from San Francisco International Airport on Sun, Apr 6, arriving at Brussels National Airport. One-way Prices start from MYR 1,581 including taxes and charges.

      • SFO19:40
        34h 40m
        1 stop
        BRU15:20
        Tue, Apr 1|San Francisco - Brussels|Scandinavian Airlines
        MYR 1,730MYR 2,651
        35% OFF
        35% OFF
        MYR 2,651MYR 1,730

        Choose Scandinavian Airlines flights from San Francisco to Brussels. The one-way connecting flight with Scandinavian Airlines departs from San Francisco International Airport on Tue, Apr 1, arriving at Brussels National Airport. One-way Prices start from MYR 1,730 including taxes and charges.

      • SFO20:00
        28h 45m
        1 stop
        BRU09:45
        Tue, Apr 1|San Francisco - Brussels|Vueling Airlines
        MYR 1,800MYR 2,651
        32% OFF
        32% OFF
        MYR 2,651MYR 1,800

        Choose Vueling Airlines flights from San Francisco to Brussels. The one-way connecting flight with Vueling Airlines departs from San Francisco International Airport on Tue, Apr 1, arriving at Brussels National Airport. One-way Prices start from MYR 1,800 including taxes and charges.

      • SFO20:00
        16h 45m
        1 stop
        BRU21:45
        Tue, May 6|San Francisco - Brussels|Vueling Airlines
        MYR 1,877
        MYR 1,877

        Choose Vueling Airlines flights from San Francisco to Brussels. The one-way connecting flight with Vueling Airlines departs from San Francisco International Airport on Tue, May 6, arriving at Brussels National Airport. One-way Prices start from MYR 1,877 including taxes and charges.

      • SFO20:00
        28h 15m
        1 stop
        BRU09:15
        Sun, Apr 13|San Francisco - Brussels|Vueling Airlines
        MYR 1,910
        MYR 1,910

        Choose Vueling Airlines flights from San Francisco to Brussels. The one-way connecting flight with Vueling Airlines departs from San Francisco International Airport on Sun, Apr 13, arriving at Brussels National Airport. One-way Prices start from MYR 1,910 including taxes and charges.

      • SFO20:00
        36h 25m
        1 stop
        BRU17:25
        Sat, Apr 5|San Francisco - Brussels|Vueling Airlines
        MYR 2,061
        MYR 2,061

        Choose Vueling Airlines flights from San Francisco to Brussels. The one-way connecting flight with Vueling Airlines departs from San Francisco International Airport on Sat, Apr 5, arriving at Brussels National Airport. One-way Prices start from MYR 2,061 including taxes and charges.

      • SFO08:30
        14h 25m
        1 stop
        BRU07:55
        Wed, Mar 5|San Francisco - Brussels|Air Canada
        MYR 2,122
        MYR 2,122

        Choose Air Canada flights from San Francisco to Brussels. The one-way connecting flight with Air Canada departs from San Francisco International Airport on Wed, Mar 5, arriving at Brussels National Airport. One-way Prices start from MYR 2,122 including taxes and charges.

      • SFO07:10
        17h 50m
        1 stop
        BRU09:00
        Sun, Mar 16|San Francisco - Brussels|Virgin Atlantic
        MYR 2,182
        MYR 2,182

        Choose Virgin Atlantic flights from San Francisco to Brussels. The one-way connecting flight with Virgin Atlantic departs from San Francisco International Airport on Sun, Mar 16, arriving at Brussels National Airport. One-way Prices start from MYR 2,182 including taxes and charges.

      • SFO15:55
        14h 25m
        1 stop
        BRU15:20
        Wed, Apr 30|San Francisco - Brussels|United Airlines
        MYR 2,190
        MYR 2,190

        Choose United Airlines flights from San Francisco to Brussels. The one-way connecting flight with United Airlines departs from San Francisco International Airport on Wed, Apr 30, arriving at Brussels National Airport. One-way Prices start from MYR 2,190 including taxes and charges.

      • SFO16:10
        14h 10m
        1 stop
        BRU15:20
        Wed, Apr 30|San Francisco - Brussels|Virgin Atlantic
        MYR 2,190
        MYR 2,190

        Choose Virgin Atlantic flights from San Francisco to Brussels. The one-way connecting flight with Virgin Atlantic departs from San Francisco International Airport on Wed, Apr 30, arriving at Brussels National Airport. One-way Prices start from MYR 2,190 including taxes and charges.

      • SFO01:00 pm
        3h 5m
        Nonstop
        BRU02:00 pm
        Thu, Feb 20|San Francisco - Brussels|Vueling Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

San Francisco to Brussels flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA016

    American Airlines

    10:42

    SFO

    5.8h

    19:30

    JFK

    SMTWTFS
    Search

  2. AA106

    American Airlines

    19:30

    JFK

    7.3h

    07:45

    LHR

    SMTWTFS

  3. BA398

    British Airways

    15:05

    LHR

    1.3h

    17:20

    BRU

    SMTWTFS

  4. UA058

    United Airlines

    13:10

    SFO

    11.0h

    09:10

    FRA

    SMTWTFS
    Search

  5. UA9540

    United Airlines

    13:35

    FRA

    1.2h

    14:45

    LIN

    SMTWT-S

  6. AZ154

    ITA Airways

    17:55

    LIN

    1.6h

    19:30

    BRU

    SMTWT-S

  7. AA1123

    American Airlines

    14:37

    SFO

    3.5h

    20:09

    DFW

    SMTWTFS
    Search

  8. AA078

    American Airlines

    21:06

    DFW

    9.0h

    12:05

    LHR

    SMTWTFS

  9. SN2096

    Brussels Airlines

    17:50

    LHR

    1.2h

    20:00

    BRU

    SMTWT-S

  10. LH455

    Lufthansa

    14:40

    SFO

    10.8h

    10:25

    FRA

    SMTWTFS
    Search

  11. LH274

    Lufthansa

    15:40

    FRA

    1.3h

    16:55

    LIN

    SMTWTFS

  12. SN3150

    Brussels Airlines

    18:50

    LIN

    1.5h

    20:20

    BRU

    SMTWT-S

  13. LH455

    Lufthansa

    14:40

    SFO

    10.8h

    10:25

    FRA

    SMTWTFS
    Search

  14. LH280

    Lufthansa

    13:00

    FRA

    1.3h

    14:15

    LIN

    SMTWT-S

  15. AZ154

    ITA Airways

    17:55

    LIN

    1.6h

    19:30

    BRU

    SMTWT-S

  16. UA8828

    United Airlines

    14:40

    SFO

    10.8h

    10:25

    FRA

    SMTWTFS
    Search

  17. LH5668

    Lufthansa

    11:30

    FRA

    1.3h

    12:45

    LIN

    SMTWTFS

  18. AZ154

    ITA Airways

    17:55

    LIN

    1.6h

    19:30

    BRU

    SMTWT-S

  19. UA8828

    United Airlines

    14:40

    SFO

    10.8h

    10:25

    FRA

    SMTWTFS
    Search

  20. UA9540

    United Airlines

    13:35

    FRA

    1.2h

    14:45

    LIN

    SMTWT-S

  21. AZ154

    ITA Airways

    17:55

    LIN

    1.6h

    19:30

    BRU

    SMTWT-S

  22. VS020

    Virgin Atlantic

    16:10

    SFO

    10.3h

    10:30

    LHR

    SM-WTFS
    Search

  23. BA574

    British Airways

    12:40

    LHR

    2.0h

    15:40

    LIN

    SMTWT-S

  24. AZ154

    ITA Airways

    17:55

    LIN

    1.6h

    19:30

    BRU

    SMTWT-S

  25. LX039

    Swiss Airlines

    19:25

    SFO

    11.1h

    15:30

    ZRH

    SMTWTFS
    Search

  26. LX1622

    Swiss Airlines

    17:25

    ZRH

    0.9h

    18:20

    MXP

    SMTWT-S

  27. SN3160

    Brussels Airlines

    21:45

    MXP

    1.5h

    23:15

    BRU

    SMT-T-S

  28. LH459

    Lufthansa

    21:05

    SFO

    11.1h

    17:10

    MUC

    SM-WTFS
    Search

  29. LH9514

    Lufthansa

    17:45

    MUC

    1.2h

    18:55

    MXP

    SMTWTF-

  30. SN3160

    Brussels Airlines

    21:45

    MXP

    1.5h

    23:15

    BRU

    SMT-T-S
Find more flights and airlines

Find the best time to fly from San Francisco to Brussels

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Airlines Flying from San Francisco to Brussels

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
TAP Air Portugal logoTAP Air Portugal

FAQ

  • When are flight tickets from San Francisco (SFO) to Brussels (BRU) the cheapest?

    Airlines adjust prices for flights from San Francisco to Brussels based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from San Francisco (SFO) to Brussels (BRU) cost?

    According to Trip.com's data, the lowest price is around MYR 5,965.

  • What is the transportation method from the main airport to downtown in Brussels?

    • The distance from Brussels National Airport to downtown is about 10 km. It takes about 30 minutes by taxi.
    • The distance from Brussels South Charleroi Airport to downtown is about 43 km. It takes about 1 hour by taxi.

How to find a cheap flight from San Francisco to Brussels

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Francisco to Brussels. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from San Francisco to Brussels

Cheapest nonstop flight priceMYR 1,581
Off-season for travelApril
Peak season for travelMay
Flight distance8,893.49 km
Popular airlineAer Lingus

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.