App
Customer Support
AED
Find Bookings
Trip.com
>
Cheap Flights
>
Bolivia
>
Santa Cruz
>
Flights from Panama City to Santa Cruz
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from Panama City to Santa Cruz Starting at AED 468

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • Cheapest nonstop
        PTY16:04
        5h
        Nonstop
        VVI22:04
        Mon, Feb 17|Panama City - Santa Cruz|Copa Airlines
        AED 2,392AED 3,124
        23% OFF
        23% OFF
        AED 3,124AED 2,392

        Choose Copa Airlines flights from Panama City to Santa Cruz. The one-way direct flight with Copa Airlines departs from Tocumen International Airport on Mon, Feb 17, arriving at Viru Viru International Airport. One-way Prices start from AED 2,392 including taxes and charges.

      • PTY21:43
        5h 1m
        Nonstop
        VVI03:44
        Fri, Mar 7|Panama City - Santa Cruz|Copa Airlines
        AED 2,405AED 3,124
        23% OFF
        23% OFF
        AED 3,124AED 2,405

        Choose Copa Airlines flights from Panama City to Santa Cruz. The one-way direct flight with Copa Airlines departs from Tocumen International Airport on Fri, Mar 7, arriving at Viru Viru International Airport. One-way Prices start from AED 2,405 including taxes and charges.

      • PTY11:05
        13h 45m
        1 stop
        VVI01:50
        Mon, Mar 31|Panama City - Santa Cruz|avianca
        AED 468AED 3,124
        85% OFF
        85% OFF
        AED 3,124AED 468

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Mon, Mar 31, arriving at Viru Viru International Airport. One-way Prices start from AED 468 including taxes and charges.

      • PTY17:25
        7h 35m
        1 stop
        VVI02:00
        Sat, Mar 15|Panama City - Santa Cruz|avianca
        AED 511
        AED 511

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Sat, Mar 15, arriving at Viru Viru International Airport. One-way Prices start from AED 511 including taxes and charges.

      • PTY11:05
        13h 45m
        1 stop
        VVI01:50
        Fri, Apr 25|Panama City - Santa Cruz|avianca
        AED 512
        AED 512

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Fri, Apr 25, arriving at Viru Viru International Airport. One-way Prices start from AED 512 including taxes and charges.

      • PTY11:25
        13h 35m
        1 stop
        VVI02:00
        Mon, Feb 17|Panama City - Santa Cruz|avianca
        AED 514
        AED 514

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Mon, Feb 17, arriving at Viru Viru International Airport. One-way Prices start from AED 514 including taxes and charges.

      • PTY11:05
        13h 45m
        1 stop
        VVI01:50
        Sun, Mar 30|Panama City - Santa Cruz|avianca
        AED 515
        AED 515

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Sun, Mar 30, arriving at Viru Viru International Airport. One-way Prices start from AED 515 including taxes and charges.

      • PTY11:25
        13h 35m
        1 stop
        VVI02:00
        Mon, Mar 10|Panama City - Santa Cruz|avianca
        AED 516
        AED 516

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Mon, Mar 10, arriving at Viru Viru International Airport. One-way Prices start from AED 516 including taxes and charges.

      • PTY17:25
        7h 35m
        1 stop
        VVI02:00
        Sat, Mar 29|Panama City - Santa Cruz|avianca
        AED 520
        AED 520

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Sat, Mar 29, arriving at Viru Viru International Airport. One-way Prices start from AED 520 including taxes and charges.

      • PTY09:50
        15h
        1 stop
        VVI01:50
        Sat, Apr 26|Panama City - Santa Cruz|avianca
        AED 527
        AED 527

        Choose avianca flights from Panama City to Santa Cruz. The one-way connecting flight with avianca departs from Tocumen International Airport on Sat, Apr 26, arriving at Viru Viru International Airport. One-way Prices start from AED 527 including taxes and charges.

      • PTY01:00 pm
        3h 5m
        Nonstop
        SRZ02:00 pm
        Sat, Feb 22|Panama City - Santa Cruz|Copa Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Panama City to Santa Cruz flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AV059

    avianca

    11:25

    PTY

    1.6h

    13:00

    BOG

    --T----
    Search

  2. AV8382

    avianca

    20:50

    BOG

    4.0h

    01:50

    VVI

    SMTWTFS

  3. AV8383

    avianca

    11:25

    PTY

    1.6h

    13:00

    BOG

    S---T-S
    Search

  4. AV8382

    avianca

    20:50

    BOG

    4.0h

    01:50

    VVI

    SMTWTFS

  5. AV061

    avianca

    17:25

    PTY

    1.5h

    18:55

    BOG

    -M-W-F-
    Search

  6. AV8382

    avianca

    20:50

    BOG

    4.0h

    01:50

    VVI

    SMTWTFS
Find more flights and airlines

Find the best time to fly from Panama City to Santa Cruz

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight tickets from Panama City (PTY) to Santa Cruz (SRZ) the cheapest?

    Airlines adjust prices for flights from Panama City to Santa Cruz based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Panama City (PTY) to Santa Cruz (SRZ) cost?

    According to Trip.com's data, the lowest price is around AED 1,407.

  • How long does it take to fly from Panama City (PTY) to Santa Cruz (SRZ) and what is the distance?

    It takes around 4 hours 54 minutes to fly from Panama City (PTY) to Santa Cruz (SRZ).

  • What is the transportation method from the main airport to downtown in Santa Cruz?

    • The distance from Viru Viru International Airport to downtown is about 17 km. It takes about 30 minutes by taxi.

  • What are the most popular airlines that fly from Panama City (PTY) to Santa Cruz (SRZ)?

    Airlines with flights from Panama City (PTY) to Santa Cruz (SRZ): Copa Airlines and United Airlines.

How to find a cheap flight from Panama City to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Santa Cruz. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Panama City to Santa Cruz

Cheapest nonstop flight priceAED 467
Cheapest round-trip ticket priceAED 1,172
Off-season for travelMarch
Peak season for travelJanuary
Flight distance3,476.98 km
Average flight time4 hours 54 minutes
Popular airlineavianca

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.