App
Customer Support
EUR
Find Bookings
Trip.com
>
Cheap Flights
>
South Africa
>
Gauteng
>
Johannesburg
>
Flights from Panama City to Johannesburg
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from Panama City to Johannesburg Starting at €1,112

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • Round-trip
      • ECP16:55
        41h 40m
        2 stops
        JNB18:35
        Mon, Mar 3|Panama City - Johannesburg|United Airlines
        JNB22:00
        46h 17m
        2 stops
        ECP13:17
        Sun, Mar 9|Johannesburg - Panama City|United Airlines
        €1,112€2,308
        52% OFF
        52% OFF
        €2,308€1,112

        Choose United Airlines flights from Panama City to Johannesburg. The one-way connecting flight with United Airlines departs from Northwest Florida Beaches International Airport on Mon, Mar 3-Sun, Mar 9, arriving at O. R. Tambo International Airport. One-way Prices start from €1,112 including taxes and charges.

      • ECP13:23
        22h 12m
        2 stops
        JNB18:35
        Tue, Mar 11|Panama City - Johannesburg|United Airlines
        JNB22:00
        28h 52m
        2 stops
        ECP19:52
        Tue, Mar 18|Johannesburg - Panama City|United Airlines
        €1,199€2,308
        48% OFF
        48% OFF
        €2,308€1,199

        Choose United Airlines flights from Panama City to Johannesburg. The one-way connecting flight with United Airlines departs from Northwest Florida Beaches International Airport on Tue, Mar 11-Tue, Mar 18, arriving at O. R. Tambo International Airport. One-way Prices start from €1,199 including taxes and charges.

      • ECP09:00
        25h 35m
        2 stops
        JNB18:35
        Thu, Feb 27|Panama City - Johannesburg|United Airlines
        JNB22:00
        31h 52m
        2 stops
        ECP21:52
        Wed, Mar 5|Johannesburg - Panama City|United Airlines
        €1,275€2,308
        45% OFF
        45% OFF
        €2,308€1,275

        Choose United Airlines flights from Panama City to Johannesburg. The one-way connecting flight with United Airlines departs from Northwest Florida Beaches International Airport on Thu, Feb 27-Wed, Mar 5, arriving at O. R. Tambo International Airport. One-way Prices start from €1,275 including taxes and charges.

      • ECP06:15
        28h 30m
        2 stops
        JNB17:45
        Tue, Apr 1|Panama City - Johannesburg|United Airlines
        JNB19:00
        32h 9m
        2 stops
        ECP20:09
        Tue, Apr 8|Johannesburg - Panama City|United Airlines
        €1,474
        €1,474

        Choose United Airlines flights from Panama City to Johannesburg. The one-way connecting flight with United Airlines departs from Northwest Florida Beaches International Airport on Tue, Apr 1-Tue, Apr 8, arriving at O. R. Tambo International Airport. One-way Prices start from €1,474 including taxes and charges.

      • ECP12:50
        38h 40m
        2 stops
        JNB11:30
        Thu, Feb 27|Panama City - Johannesburg|Delta Air Lines
        JNB19:30
        32h 17m
        2 stops
        ECP19:47
        Wed, Mar 5|Johannesburg - Panama City|Virgin Atlantic
        €1,525
        €1,525

        Choose Delta Air Lines flights from Panama City to Johannesburg. The one-way connecting flight with Delta Air Lines departs from Northwest Florida Beaches International Airport on Thu, Feb 27-Wed, Mar 5, arriving at O. R. Tambo International Airport. One-way Prices start from €1,525 including taxes and charges.

      • ECP17:34
        33h 56m
        2 stops
        JNB11:30
        Thu, Feb 27|Panama City - Johannesburg|Virgin Atlantic
        JNB19:30
        32h 17m
        2 stops
        ECP19:47
        Wed, Mar 5|Johannesburg - Panama City|Virgin Atlantic
        €1,525
        €1,525

        Choose Virgin Atlantic flights from Panama City to Johannesburg. The one-way connecting flight with Virgin Atlantic departs from Northwest Florida Beaches International Airport on Thu, Feb 27-Wed, Mar 5, arriving at O. R. Tambo International Airport. One-way Prices start from €1,525 including taxes and charges.

      • ECP15:38
        39h 57m
        2 stops
        JNB15:35
        Thu, Feb 27|Panama City - Johannesburg|Qatar Airways
        JNB08:50
        37h 59m
        2 stops
        ECP14:49
        Wed, Mar 5|Johannesburg - Panama City|Qatar Airways
        €1,559
        €1,559

        Choose Qatar Airways flights from Panama City to Johannesburg. The one-way connecting flight with Qatar Airways departs from Northwest Florida Beaches International Airport on Thu, Feb 27-Wed, Mar 5, arriving at O. R. Tambo International Airport. One-way Prices start from €1,559 including taxes and charges.

      • ECP09:00
        25h 35m
        2 stops
        JNB18:35
        Sat, Mar 1|Panama City - Johannesburg|United Airlines
        JNB19:35
        34h 17m
        2 stops
        ECP21:52
        Fri, Mar 7|Johannesburg - Panama City|United Airlines
        €1,630
        €1,630

        Choose United Airlines flights from Panama City to Johannesburg. The one-way connecting flight with United Airlines departs from Northwest Florida Beaches International Airport on Sat, Mar 1-Fri, Mar 7, arriving at O. R. Tambo International Airport. One-way Prices start from €1,630 including taxes and charges.

      • ECP06:30
        28h 5m
        2 stops
        JNB18:35
        Fri, Feb 28|Panama City - Johannesburg|United Airlines
        JNB22:00
        47h 17m
        2 stops
        ECP13:17
        Thu, Mar 6|Johannesburg - Panama City|United Airlines
        €1,665
        €1,665

        Choose United Airlines flights from Panama City to Johannesburg. The one-way connecting flight with United Airlines departs from Northwest Florida Beaches International Airport on Fri, Feb 28-Thu, Mar 6, arriving at O. R. Tambo International Airport. One-way Prices start from €1,665 including taxes and charges.

      • ECP15:38
        33h 47m
        2 stops
        JNB09:25
        Mon, Mar 3|Panama City - Johannesburg|Qatar Airways
        JNB20:00
        31h 32m
        2 stops
        ECP20:32
        Sun, Mar 9|Johannesburg - Panama City|Qatar Airways
        €1,686
        €1,686

        Choose Qatar Airways flights from Panama City to Johannesburg. The one-way connecting flight with Qatar Airways departs from Northwest Florida Beaches International Airport on Mon, Mar 3-Sun, Mar 9, arriving at O. R. Tambo International Airport. One-way Prices start from €1,686 including taxes and charges.

      • ECP01:00 pm
        3h 5m
        Nonstop
        JNB02:00 pm
        Sat, Mar 1|Panama City - Johannesburg|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Panama City to Johannesburg flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. UA6035

    United Airlines

    06:40

    ECP

    2.1h

    08:47

    IAH

    SMTWTFS
    Search

  2. UA1499

    United Airlines

    12:00

    IAH

    3.8h

    16:46

    EWR

    SMTWTFS

  3. UA188

    United Airlines

    20:55

    EWR

    15.7h

    18:35

    JNB

    SMTWTFS

  4. UA6035

    United Airlines

    06:40

    ECP

    2.1h

    08:47

    IAH

    SMTWTFS
    Search

  5. UA1893

    United Airlines

    09:55

    IAH

    3.6h

    14:31

    EWR

    SMTWTFS

  6. UA188

    United Airlines

    20:55

    EWR

    15.7h

    18:35

    JNB

    SMTWTFS

  7. UA6073

    United Airlines

    09:00

    ECP

    2.1h

    11:09

    IAH

    SMTWTFS
    Search

  8. UA2608

    United Airlines

    14:30

    IAH

    3.6h

    19:08

    EWR

    SMTWTFS

  9. UA188

    United Airlines

    20:55

    EWR

    15.7h

    18:35

    JNB

    SMTWTFS

  10. UA6073

    United Airlines

    09:00

    ECP

    2.1h

    11:09

    IAH

    SMTWTFS
    Search

  11. UA1891

    United Airlines

    13:29

    IAH

    3.6h

    18:05

    EWR

    SMTWTFS

  12. UA188

    United Airlines

    20:55

    EWR

    15.7h

    18:35

    JNB

    SMTWTFS

  13. UA4255

    United Airlines

    12:34

    ECP

    2.1h

    14:40

    IAH

    SMTWTFS
    Search

  14. UA1646

    United Airlines

    16:30

    IAH

    3.5h

    20:58

    EWR

    SMTWTFS

  15. UA188

    United Airlines

    20:55

    EWR

    15.7h

    18:35

    JNB

    SMTWTFS

  16. AA1739

    American Airlines

    15:37

    ECP

    2.5h

    18:04

    DFW

    SMTWTFS
    Search

  17. QR732

    Qatar Airways

    22:50

    DFW

    14.5h

    21:20

    DOH

    SMTWTFS

  18. QR1363

    Qatar Airways

    02:35

    DOH

    8.4h

    10:00

    JNB

    SMTWTFS

  19. QR2521

    Qatar Airways

    15:42

    ECP

    2.5h

    18:10

    DFW

    SMTWTFS
    Search

  20. QR732

    Qatar Airways

    22:50

    DFW

    14.5h

    21:20

    DOH

    SMTWTFS

  21. QR1363

    Qatar Airways

    02:35

    DOH

    8.4h

    10:00

    JNB

    SMTWTFS

  22. VS2588

    Virgin Atlantic

    19:05

    ECP

    1.3h

    21:20

    ATL

    SMTWTFS
    Search

  23. VS4067

    Virgin Atlantic

    23:59

    ATL

    8.5h

    13:30

    LHR

    SMTWTFS

  24. VS449

    Virgin Atlantic

    22:15

    LHR

    11.0h

    10:15

    JNB

    SMTWTFS

  25. DL3053

    Delta Air Lines

    19:05

    ECP

    1.3h

    21:23

    ATL

    SMTWTFS
    Search

  26. VS4010

    Virgin Atlantic

    21:45

    ATL

    8.4h

    11:10

    LHR

    SMTWTFS

  27. VS449

    Virgin Atlantic

    22:15

    LHR

    11.0h

    10:15

    JNB

    SMTWTFS

  28. VS2588

    Virgin Atlantic

    19:05

    ECP

    1.3h

    21:20

    ATL

    SMTWTFS
    Search

  29. VS4010

    Virgin Atlantic

    21:45

    ATL

    8.4h

    11:10

    LHR

    SMTWTFS

  30. VS449

    Virgin Atlantic

    22:15

    LHR

    11.0h

    10:15

    JNB

    SMTWTFS
Find more flights and airlines

Find the best time to fly from Panama City to Johannesburg

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight tickets from Panama City (ECP) to Johannesburg (JNB) the cheapest?

    Airlines adjust prices for flights from Panama City to Johannesburg based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Panama City (ECP) to Johannesburg (JNB) cost?

    According to Trip.com's data, the lowest price is around €1,972.

  • What is the transportation method from the main airport to downtown in Johannesburg?

    • The distance from O. R. Tambo International Airport to downtown is about 20 km. It takes about 40 minutes by taxi.
    • The distance from Lanseria International Airport to downtown is about 32 km. It takes about 50 minutes by taxi.

How to find a cheap flight from Panama City to Johannesburg

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Johannesburg. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Panama City to Johannesburg

Off-season for travelJanuary
Peak season for travelNovember
Flight distance13,607.26 km
Popular airlineAmerican Airlines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.