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Flights from Myrtle Beach to Lafayette

Airlines operating flights from Myrtle Beach to Lafayette

To travel from Myrtle Beach to Lafayette, travellers usually fly via nearby airports in Myrtle Beach and Indianapolis. Compare airlines and fares below.
Spirit Airlines logo Spirit Airlines

There are no flights available between Myrtle Beach and Lafayette. See below for nearby flight options from Myrtle Beach to Indianapolis.

      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Tue, Dec 30 | Spirit Airlines
        IND 16:51
        7h 8m
        1 stop
        MYR 23:59
        Indianapolis - Myrtle Beach | Mon, Jan 5 | Spirit Airlines
        TRY 7,731 TRY 15,843
        51% OFF
        51% OFF
        TRY 15,843 TRY 7,731
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Fri, Dec 26 | Spirit Airlines
        IND 12:38
        5h 30m
        1 stop
        MYR 18:08
        Indianapolis - Myrtle Beach | Wed, Dec 31 | Spirit Airlines
        TRY 9,490 TRY 15,843
        40% OFF
        40% OFF
        TRY 15,843 TRY 9,490
      • MYR 14:15
        7h 20m
        1 stop
        IND 21:35
        Myrtle Beach - Indianapolis | Sat, Dec 13 | Spirit Airlines
        IND 12:03
        5h 45m
        1 stop
        MYR 17:48
        Indianapolis - Myrtle Beach | Wed, Dec 17 | Spirit Airlines
        TRY 10,306 TRY 15,843
        35% OFF
        35% OFF
        TRY 15,843 TRY 10,306
      • MYR 05:11
        4h 11m
        1 stop
        IND 09:22
        Myrtle Beach - Indianapolis | Fri, Dec 26 | American Airlines
        IND 16:51
        7h 8m
        1 stop
        MYR 23:59
        Indianapolis - Myrtle Beach | Wed, Dec 31 | Spirit Airlines
        TRY 11,980
        24% OFF
        TRY 15,843 TRY 11,980
      • MYR 14:15
        7h 20m
        1 stop
        IND 21:35
        Myrtle Beach - Indianapolis | Fri, Dec 12 | Spirit Airlines
        IND 05:15
        5h 27m
        1 stop
        MYR 10:42
        Indianapolis - Myrtle Beach | Sun, Dec 14 | American Airlines
        TRY 12,391
        22% OFF
        TRY 15,843 TRY 12,391
      • MYR 06:23
        3h 58m
        1 stop
        IND 10:21
        Myrtle Beach - Indianapolis | Thu, Feb 5 | American Airlines
        IND 06:00
        5h 35m
        1 stop
        MYR 11:35
        Indianapolis - Myrtle Beach | Sun, Feb 8 | American Airlines
        TRY 12,983
        18% OFF
        TRY 15,843 TRY 12,983
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Tue, Dec 23 | Spirit Airlines
        IND 12:38
        5h 30m
        1 stop
        MYR 18:08
        Indianapolis - Myrtle Beach | Tue, Dec 30 | Spirit Airlines
        TRY 13,086
        17% OFF
        TRY 15,843 TRY 13,086
      • MYR 18:49
        5h 17m
        1 stop
        IND 00:06
        Myrtle Beach - Indianapolis | Mon, Jan 12 | Delta Air Lines
        IND 06:00
        3h 48m
        1 stop
        MYR 09:48
        Indianapolis - Myrtle Beach | Thu, Jan 15 | Delta Air Lines
        TRY 13,570
        14% OFF
        TRY 15,843 TRY 13,570
      • MYR 06:00
        3h 48m
        1 stop
        IND 09:48
        Myrtle Beach - Indianapolis | Fri, Dec 26 | Delta Air Lines
        IND 06:00
        4h 24m
        1 stop
        MYR 10:24
        Indianapolis - Myrtle Beach | Wed, Dec 31 | Delta Air Lines
        TRY 13,805
        13% OFF
        TRY 15,843 TRY 13,805
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Fri, Dec 19 | Spirit Airlines
        IND 12:38
        5h 30m
        1 stop
        MYR 18:08
        Indianapolis - Myrtle Beach | Tue, Dec 23 | Spirit Airlines
        TRY 14,259
        10% OFF
        TRY 15,843 TRY 14,259
      • MYR 13:00
        17h 25m
        1 stop
        IND Invalid Date
        Myrtle Beach - Indianapolis | Sat, Dec 13 | Normal Airline
        IND 15:00
        6h
        Direct
        MYR 16:00
        Indianapolis - Myrtle Beach | Mon, Dec 15 | Normal Airline
        Find More Flights
        Find More Flights
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Thu, Dec 25 | Spirit Airlines
        TRY 3,857 TRY 7,415
        48% OFF
        48% OFF
        TRY 7,415 TRY 3,857
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Wed, Dec 24 | Spirit Airlines
        TRY 4,685 TRY 7,415
        37% OFF
        37% OFF
        TRY 7,415 TRY 4,685
      • MYR 18:59
        12h 44m
        1 stop
        IND 07:43
        Myrtle Beach - Indianapolis | Fri, Dec 12 | Spirit Airlines
        TRY 4,902 TRY 7,415
        34% OFF
        34% OFF
        TRY 7,415 TRY 4,902
      • MYR 06:00
        3h 48m
        1 stop
        IND 09:48
        Myrtle Beach - Indianapolis | Thu, Dec 25 | Delta Air Lines
        TRY 5,301
        28% OFF
        TRY 7,415 TRY 5,301
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Sat, Dec 20 | Spirit Airlines
        TRY 5,664
        24% OFF
        TRY 7,415 TRY 5,664
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Sun, Dec 21 | Spirit Airlines
        TRY 5,912
        20% OFF
        TRY 7,415 TRY 5,912
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Fri, Dec 26 | Spirit Airlines
        TRY 6,431
        13% OFF
        TRY 7,415 TRY 6,431
      • MYR 12:25
        7h 33m
        1 stop
        IND 19:58
        Myrtle Beach - Indianapolis | Mon, Jan 5 | Delta Air Lines
        TRY 6,546
        12% OFF
        TRY 7,415 TRY 6,546
      • MYR 12:30
        19h 13m
        1 stop
        IND 07:43
        Myrtle Beach - Indianapolis | Fri, Dec 12 | Delta Air Lines
        TRY 6,637
        10% OFF
        TRY 7,415 TRY 6,637
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Tue, Dec 23 | Spirit Airlines
        TRY 6,673
        10% OFF
        TRY 7,415 TRY 6,673
      • MYR 13:00
        17h 25m
        1 stop
        IND Invalid Date
        Myrtle Beach - Indianapolis | Sat, Dec 13 | Normal Airline
        Find More Flights
        Find More Flights

Displayed flight fares from Myrtle Beach to Lafayette are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Myrtle Beach to Lafayette

Check flight details from Myrtle Beach to Indianapolis: distance, average duration, and cheapest month to plan your trip from Myrtle Beach to Lafayette.

Cheapest one-way flight priceTRY 3,857
Cheapest round-trip ticket priceTRY 7,731
Off-season for travelAugust
Peak season for travelJuly
Flight distance934.41 km
Average flight time3 hours 55 minutes
Popular airlineSpirit Airlines

Find the best time to fly from Myrtle Beach to Lafayette

Check price trends for flights from Myrtle Beach to Indianapolis to find the cheapest month to travel from Myrtle Beach to Lafayette.

Cheapest flights
From price
Search
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Myrtle Beach to Lafayette, calculated over the upcoming 10 weeks.

Flight FAQs

FAQs about flights from Myrtle Beach to Lafayette (no local airports)

  • What are the cheapest flights from Myrtle Beach to Indianapolis (MYR-IND)?

    Based on Trip.com data, Spirit Airlines offers one-way fares as low as TRY 3,857 on Cheapest nonstop routes (e.g. MYR to IND on Thu, Dec 25), while Spirit Airlines offers Cheapest nonstop round-trips from TRY 7,731 departing on Tue, Dec 30 and returning on Mon, Jan 5.
  • At the moment, several airlines serve connecting flights from Myrtle Beach to Indianapolis, including: Spirit Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • It takes around 3 hours 55 minutes to fly from Myrtle Beach (MYR) to Indianapolis (IND).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Myrtle Beach to Indianapolis is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Myrtle Beach to Indianapolis, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Dec 25, with one-way flights priced at just TRY 3,857.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Spirit Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Indianapolis travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Myrtle Beach to Indianapolis is August, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Myrtle Beach to Indianapolis on December 30, 2025 with Spirit Airlines, with prices starting at TRY 7,730.
  • You can land at any one of the following hubs in Indianapolis, with Myrtle Beach International Airport to Indianapolis International Airport (MYR-IND) is by far the most common option on this route: Indianapolis International Airport (IND).
  • The time difference between Indianapolis and Myrtle Beach is 0h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.