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Flights from Myrtle Beach to Buffalo

Airlines operating flights from Myrtle Beach to Buffalo

Choose from 1 airlines flying from Myrtle Beach to Buffalo, including Delta Air Lines, and . Spirit Airlines currently offers the cheapest ticket on this route.
Delta Air Lines logo Delta Air Lines

Find the cheapest flight options from Myrtle Beach to Buffalo over the next three months. Book one-way tickets from ILS 511 and round-trip tickets from ILS 900.

      • MYR 19:13
        14h 41m
        1 stop
        BUF 09:54
        Myrtle Beach - Buffalo | Tue, Jan 6 | Spirit Airlines
        BUF 05:12
        6h 36m
        1 stop
        MYR 11:48
        Buffalo - Myrtle Beach | Tue, Jan 13 | American Airlines
        ILS 900 ILS 1,195
        25% OFF
        25% OFF
        ILS 1,195 ILS 900
      • MYR 06:23
        5h 45m
        1 stop
        BUF 12:08
        Myrtle Beach - Buffalo | Thu, Jan 22 | American Airlines
        BUF 12:58
        5h 51m
        1 stop
        MYR 18:49
        Buffalo - Myrtle Beach | Sat, Jan 24 | American Airlines
        ILS 904 ILS 1,195
        24% OFF
        24% OFF
        ILS 1,195 ILS 904
      • MYR 06:23
        5h 45m
        1 stop
        BUF 12:08
        Myrtle Beach - Buffalo | Thu, Feb 5 | American Airlines
        BUF 07:00
        4h 35m
        1 stop
        MYR 11:35
        Buffalo - Myrtle Beach | Mon, Feb 9 | American Airlines
        ILS 904 ILS 1,195
        24% OFF
        24% OFF
        ILS 1,195 ILS 904
      • MYR 12:25
        4h 30m
        1 stop
        BUF 16:55
        Myrtle Beach - Buffalo | Tue, Jan 6 | Delta Air Lines
        BUF 06:00
        5h 35m
        1 stop
        MYR 11:35
        Buffalo - Myrtle Beach | Tue, Jan 13 | Delta Air Lines
        ILS 915
        23% OFF
        ILS 1,195 ILS 915
      • MYR 17:15
        5h 38m
        1 stop
        BUF 22:53
        Myrtle Beach - Buffalo | Tue, Dec 30 | Delta Air Lines
        BUF 06:16
        5h 45m
        1 stop
        MYR 12:01
        Buffalo - Myrtle Beach | Mon, Jan 5 | Delta Air Lines
        ILS 931
        22% OFF
        ILS 1,195 ILS 931
      • MYR 18:56
        5h 3m
        1 stop
        BUF 23:59
        Myrtle Beach - Buffalo | Tue, Dec 16 | Delta Air Lines
        BUF 06:00
        4h 24m
        1 stop
        MYR 10:24
        Buffalo - Myrtle Beach | Mon, Dec 22 | Delta Air Lines
        ILS 967
        19% OFF
        ILS 1,195 ILS 967
      • MYR 17:29
        6h 12m
        1 stop
        BUF 23:41
        Myrtle Beach - Buffalo | Tue, Jan 6 | American Airlines
        BUF 18:32
        5h 25m
        1 stop
        MYR 23:57
        Buffalo - Myrtle Beach | Tue, Jan 13 | American Airlines
        ILS 990
        17% OFF
        ILS 1,195 ILS 990
      • MYR 05:00
        6h 3m
        1 stop
        BUF 11:03
        Myrtle Beach - Buffalo | Thu, Dec 11 | American Airlines
        BUF 07:04
        4h 35m
        1 stop
        MYR 11:39
        Buffalo - Myrtle Beach | Tue, Dec 16 | American Airlines
        ILS 1,030
        14% OFF
        ILS 1,195 ILS 1,030
      • MYR 17:41
        16h 6m
        1 stop
        BUF 09:47
        Myrtle Beach - Buffalo | Mon, Dec 15 | Spirit Airlines
        BUF 06:00
        17h 59m
        1 stop
        MYR 23:59
        Buffalo - Myrtle Beach | Fri, Dec 19 | Delta Air Lines
        ILS 1,048
        12% OFF
        ILS 1,195 ILS 1,048
      • MYR 10:32
        6h 46m
        1 stop
        BUF 17:18
        Myrtle Beach - Buffalo | Fri, Dec 12 | Delta Air Lines
        BUF 06:12
        4h 22m
        1 stop
        MYR 10:34
        Buffalo - Myrtle Beach | Tue, Dec 16 | Delta Air Lines
        ILS 1,063
        11% OFF
        ILS 1,195 ILS 1,063
      • MYR 13:00
        17h 25m
        1 stop
        BUF Invalid Date
        Myrtle Beach - Buffalo | Fri, Dec 12 | Normal Airline
        BUF 15:00
        6h
        Direct
        MYR 16:00
        Buffalo - Myrtle Beach | Sun, Dec 14 | Normal Airline
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Displayed flight fares from Myrtle Beach to Buffalo are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Myrtle Beach to Buffalo

The distance between Myrtle Beach and Buffalo is 1,027.71 km. Based on Trip.com's data, travel demand peaks in December. The off-season for travel is September.

Cheapest one-way flight priceILS 511
Cheapest round-trip ticket priceILS 900
Off-season for travelSeptember
Peak season for travelDecember
Flight distance1,027.71 km
Popular airlineDelta Air Lines

Find the best time to fly from Myrtle Beach to Buffalo

The cheapest time for Myrtle Beach to Buffalo flights: Feb 8 to Feb 15 — one way flight prices from ILS 479.

Cheapest flights
From price
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  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Myrtle Beach to Buffalo, calculated over the upcoming 10 weeks.

Flight FAQs

  • What are the cheapest flights from Myrtle Beach to Buffalo (MYR-BUF)?

    Based on Trip.com data, Spirit Airlines offers one-way fares as low as ILS 511 on Cheapest nonstop routes (e.g. MYR to BUF on Sun, Dec 14), while Spirit Airlines offers Cheapest nonstop round-trips from ILS 900 departing on Tue, Jan 6 and returning on Tue, Jan 13.
  • At the moment, several airlines serve connecting flights from Myrtle Beach to Buffalo, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Myrtle Beach to Buffalo is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Myrtle Beach to Buffalo, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sun, Dec 14, with one-way flights priced at just ILS 511.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Spirit Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Buffalo travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Myrtle Beach to Buffalo is September, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Myrtle Beach to Buffalo on December 12, 2025 with Spirit Airlines, with prices starting at ILS 344.
  • You can land at any one of the following hubs in Buffalo, with Myrtle Beach International Airport to Buffalo Niagara International Airport (MYR-BUF) is by far the most common option on this route: Buffalo Niagara International Airport (BUF).
  • The time difference between Buffalo and Myrtle Beach is 0h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.