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Flights from Mexico City to Santa Cruz
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Flights from Mexico City to Santa Cruz Starting at €261

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • MEX13:50
        10h 10m
        1 stop
        VVI02:00
        Tue, Feb 25|Mexico City - Santa Cruz|avianca
        €261€313
        17% OFF
        17% OFF
        €313€261

        Choose avianca flights from Mexico City to Santa Cruz. The one-way connecting flight with avianca departs from Benito Juárez International Airport on Tue, Feb 25, arriving at Viru Viru International Airport. One-way Prices start from €261 including taxes and charges.

      • MEX21:45
        29h
        1 stop
        VVI04:45
        Sat, Mar 22|Mexico City - Santa Cruz|Volaris
        €264€313
        16% OFF
        16% OFF
        €313€264

        Choose Volaris flights from Mexico City to Santa Cruz. The one-way connecting flight with Volaris departs from Benito Juárez International Airport on Sat, Mar 22, arriving at Viru Viru International Airport. One-way Prices start from €264 including taxes and charges.

      • MEX16:05
        10h 40m
        1 stop
        VVI04:45
        Sat, Mar 22|Mexico City - Santa Cruz|LATAM Airlines
        €283€313
        10% OFF
        10% OFF
        €313€283

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Sat, Mar 22, arriving at Viru Viru International Airport. One-way Prices start from €283 including taxes and charges.

      • MEX15:10
        11h 25m
        1 stop
        VVI04:35
        Mon, Apr 21|Mexico City - Santa Cruz|LATAM Airlines
        €283
        €283

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Mon, Apr 21, arriving at Viru Viru International Airport. One-way Prices start from €283 including taxes and charges.

      • MEX05:00
        19h
        1 stop
        VVI02:00
        Mon, Mar 10|Mexico City - Santa Cruz|avianca
        €284
        €284

        Choose avianca flights from Mexico City to Santa Cruz. The one-way connecting flight with avianca departs from Benito Juárez International Airport on Mon, Mar 10, arriving at Viru Viru International Airport. One-way Prices start from €284 including taxes and charges.

      • MEX16:05
        10h 40m
        1 stop
        VVI04:45
        Mon, Mar 10|Mexico City - Santa Cruz|LATAM Airlines
        €284
        €284

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Mon, Mar 10, arriving at Viru Viru International Airport. One-way Prices start from €284 including taxes and charges.

      • MEX15:10
        11h 25m
        1 stop
        VVI04:35
        Thu, Apr 17|Mexico City - Santa Cruz|LATAM Airlines
        €284
        €284

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Thu, Apr 17, arriving at Viru Viru International Airport. One-way Prices start from €284 including taxes and charges.

      • MEX15:10
        11h 25m
        1 stop
        VVI04:35
        Thu, Apr 3|Mexico City - Santa Cruz|LATAM Airlines
        €284
        €284

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Thu, Apr 3, arriving at Viru Viru International Airport. One-way Prices start from €284 including taxes and charges.

      • MEX16:05
        10h 40m
        1 stop
        VVI04:45
        Sat, Mar 8|Mexico City - Santa Cruz|LATAM Airlines
        €284
        €284

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Sat, Mar 8, arriving at Viru Viru International Airport. One-way Prices start from €284 including taxes and charges.

      • MEX16:05
        10h 40m
        1 stop
        VVI04:45
        Wed, Mar 26|Mexico City - Santa Cruz|LATAM Airlines
        €284
        €284

        Choose LATAM Airlines flights from Mexico City to Santa Cruz. The one-way connecting flight with LATAM Airlines departs from Benito Juárez International Airport on Wed, Mar 26, arriving at Viru Viru International Airport. One-way Prices start from €284 including taxes and charges.

      • MEX01:00 pm
        3h 5m
        Nonstop
        SRZ02:00 pm
        Thu, Feb 27|Mexico City - Santa Cruz|avianca
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Find the best time to fly from Mexico City to Santa Cruz

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight tickets from Mexico City (MEX) to Santa Cruz (SRZ) the cheapest?

    Airlines adjust prices for flights from Mexico City to Santa Cruz based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Mexico City (MEX) to Santa Cruz (SRZ) cost?

    According to Trip.com's data, the lowest price is around €655.

  • What is the transportation method from the main airport to downtown in Santa Cruz?

    • The distance from Viru Viru International Airport to downtown is about 17 km. It takes about 30 minutes by taxi.

How to find a cheap flight from Mexico City to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mexico City to Santa Cruz. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Mexico City to Santa Cruz

Cheapest nonstop flight price€261
Off-season for travelFebruary
Peak season for travelNovember
Flight distance5,702.49 km
Popular airlineAeromexico

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