App
Customer Support
AED
Find Bookings
Trip.com
>
Cheap Flights
>
United States
>
California
>
San Diego
>
Flights from La Serena to San Diego
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from La Serena to San Diego Starting at AED 3,762

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • Round-trip
      • LSC14:34
        24h 37m
        2 stops
        SAN11:11
        Mon, Mar 17|La Serena - San Diego|JetSMART Airlines
        SAN12:17
        25h 30m
        2 stops
        LSC17:47
        Mon, Mar 24|San Diego - La Serena|United Airlines
        AED 3,762AED 5,801
        35% OFF
        35% OFF
        AED 5,801AED 3,762

        Choose JetSMART Airlines flights from La Serena to San Diego. The one-way connecting flight with JetSMART Airlines departs from La Florida Airport on Mon, Mar 17-Mon, Mar 24, arriving at San Diego International Airport. One-way Prices start from AED 3,762 including taxes and charges.

      • LSC10:51
        31h 12m
        2 stops
        SAN14:03
        Wed, Mar 12|La Serena - San Diego|JetSMART Airlines
        SAN06:15
        32h 16m
        2 stops
        LSC18:31
        Tue, Mar 18|San Diego - La Serena|United Airlines
        AED 4,583AED 5,801
        21% OFF
        21% OFF
        AED 5,801AED 4,583

        Choose JetSMART Airlines flights from La Serena to San Diego. The one-way connecting flight with JetSMART Airlines departs from La Florida Airport on Wed, Mar 12-Tue, Mar 18, arriving at San Diego International Airport. One-way Prices start from AED 4,583 including taxes and charges.

      • LSC13:12
        26h 59m
        2 stops
        SAN11:11
        Thu, Feb 20|La Serena - San Diego|JetSMART Airlines
        SAN17:42
        41h 58m
        2 stops
        LSC16:40
        Thu, Feb 27|San Diego - La Serena|United Airlines
        AED 4,616AED 5,801
        20% OFF
        20% OFF
        AED 5,801AED 4,616

        Choose JetSMART Airlines flights from La Serena to San Diego. The one-way connecting flight with JetSMART Airlines departs from La Florida Airport on Thu, Feb 20-Thu, Feb 27, arriving at San Diego International Airport. One-way Prices start from AED 4,616 including taxes and charges.

      • LSC09:45
        30h 26m
        2 stops
        SAN11:11
        Thu, Feb 20|La Serena - San Diego|LATAM Airlines
        SAN17:42
        44h 13m
        2 stops
        LSC18:55
        Thu, Feb 27|San Diego - La Serena|United Airlines
        AED 4,672
        AED 4,672

        Choose LATAM Airlines flights from La Serena to San Diego. The one-way connecting flight with LATAM Airlines departs from La Florida Airport on Thu, Feb 20-Thu, Feb 27, arriving at San Diego International Airport. One-way Prices start from AED 4,672 including taxes and charges.

      • LSC12:42
        27h 29m
        2 stops
        SAN11:11
        Thu, Feb 20|La Serena - San Diego|Sky Airline
        SAN10:31
        41h 30m
        2 stops
        LSC09:01
        Thu, Feb 27|San Diego - La Serena|United Airlines
        AED 5,279
        AED 5,279

        Choose Sky Airline flights from La Serena to San Diego. The one-way connecting flight with Sky Airline departs from La Florida Airport on Thu, Feb 20-Thu, Feb 27, arriving at San Diego International Airport. One-way Prices start from AED 5,279 including taxes and charges.

      • LSC01:00 pm
        3h 5m
        Nonstop
        SAN02:00 pm
        Thu, Feb 27|La Serena - San Diego|JetSMART Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

La Serena to San Diego flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. LA323

    LATAM Airlines

    09:45

    LSC

    0.9h

    10:40

    SCL

    --TW---
    Search

  2. UA846

    United Airlines

    22:45

    SCL

    8.7h

    05:25

    IAH

    SMTWTFS

  3. UA2491

    United Airlines

    09:30

    IAH

    3.7h

    11:11

    SAN

    SMTWTFS

  4. H2209

    Sky Airline

    12:42

    LSC

    1.0h

    13:40

    SCL

    SM-W--S
    Search

  5. UA846

    United Airlines

    22:45

    SCL

    8.7h

    05:25

    IAH

    SMTWTFS

  6. UA2491

    United Airlines

    09:30

    IAH

    3.7h

    11:11

    SAN

    SMTWTFS

  7. JA617

    JetSMART Airlines

    13:12

    LSC

    1.0h

    14:10

    SCL

    SMTWT--
    Search

  8. UA846

    United Airlines

    22:45

    SCL

    8.7h

    05:25

    IAH

    SMTWTFS

  9. UA2486

    United Airlines

    12:10

    IAH

    3.7h

    13:53

    SAN

    SMTWTFS

  10. JA617

    JetSMART Airlines

    13:12

    LSC

    1.0h

    14:10

    SCL

    SMTWT--
    Search

  11. UA846

    United Airlines

    22:45

    SCL

    8.7h

    05:25

    IAH

    SMTWTFS

  12. UA2491

    United Airlines

    09:30

    IAH

    3.7h

    11:11

    SAN

    SMTWTFS
Find more flights and airlines

Find the best time to fly from La Serena to San Diego

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight tickets from La Serena (LSC) to San Diego (SAN) the cheapest?

    Airlines adjust prices for flights from La Serena to San Diego based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from La Serena (LSC) to San Diego (SAN) cost?

    According to Trip.com's data, the lowest price is around AED 3,060.

  • What is the transportation method from the main airport to downtown in San Diego?

    • The distance from San Diego International Airport to downtown is about 3 km. It takes about 20 minutes by taxi.

How to find a cheap flight from La Serena to San Diego

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from La Serena to San Diego. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from La Serena to San Diego

Off-season for travelJuly
Peak season for travelApril
Flight distance8,483.45 km
Popular airlineJetSMART

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.