App
Customer Support
EUR
Find Bookings
Trip.com
>
Cheap Flights
>
United States
>
California
>
San Diego
>
Flights from Greenville to San Diego
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from Greenville to San Diego Starting at €168

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • GSP17:13
        8h 35m
        1 stop
        SAN22:48
        Tue, Mar 18|Greenville - San Diego|Delta Air Lines
        €168€291
        42% OFF
        42% OFF
        €291€168

        Choose Delta Air Lines flights from Greenville to San Diego. The one-way connecting flight with Delta Air Lines departs from Greenville-Spartanburg International Airport on Tue, Mar 18, arriving at San Diego International Airport. One-way Prices start from €168 including taxes and charges.

      • GSP11:54
        9h 57m
        1 stop
        SAN18:51
        Thu, Mar 6|Greenville - San Diego|Delta Air Lines
        €170€291
        42% OFF
        42% OFF
        €291€170

        Choose Delta Air Lines flights from Greenville to San Diego. The one-way connecting flight with Delta Air Lines departs from Greenville-Spartanburg International Airport on Thu, Mar 6, arriving at San Diego International Airport. One-way Prices start from €170 including taxes and charges.

      • GSP17:31
        6h 34m
        1 stop
        SAN21:05
        Wed, Feb 26|Greenville - San Diego|Delta Air Lines
        €178€291
        39% OFF
        39% OFF
        €291€178

        Choose Delta Air Lines flights from Greenville to San Diego. The one-way connecting flight with Delta Air Lines departs from Greenville-Spartanburg International Airport on Wed, Feb 26, arriving at San Diego International Airport. One-way Prices start from €178 including taxes and charges.

      • GSP19:20
        6h 59m
        1 stop
        SAN23:19
        Thu, Feb 27|Greenville - San Diego|Delta Air Lines
        €178
        €178

        Choose Delta Air Lines flights from Greenville to San Diego. The one-way connecting flight with Delta Air Lines departs from Greenville-Spartanburg International Airport on Thu, Feb 27, arriving at San Diego International Airport. One-way Prices start from €178 including taxes and charges.

      • GSP17:31
        8h 48m
        1 stop
        SAN23:19
        Fri, Mar 7|Greenville - San Diego|Delta Air Lines
        €195
        €195

        Choose Delta Air Lines flights from Greenville to San Diego. The one-way connecting flight with Delta Air Lines departs from Greenville-Spartanburg International Airport on Fri, Mar 7, arriving at San Diego International Airport. One-way Prices start from €195 including taxes and charges.

      • GSP05:40
        7h 58m
        1 stop
        SAN10:38
        Sat, Mar 1|Greenville - San Diego|Delta Air Lines
        €207
        €207

        Choose Delta Air Lines flights from Greenville to San Diego. The one-way connecting flight with Delta Air Lines departs from Greenville-Spartanburg International Airport on Sat, Mar 1, arriving at San Diego International Airport. One-way Prices start from €207 including taxes and charges.

      • GSP14:53
        9h 9m
        1 stop
        SAN21:02
        Thu, Mar 6|Greenville - San Diego|United Airlines
        €212
        €212

        Choose United Airlines flights from Greenville to San Diego. The one-way connecting flight with United Airlines departs from Greenville-Spartanburg International Airport on Thu, Mar 6, arriving at San Diego International Airport. One-way Prices start from €212 including taxes and charges.

      • GSP19:47
        7h 11m
        1 stop
        SAN23:58
        Sun, Mar 16|Greenville - San Diego|American Airlines
        €213
        €213

        Choose American Airlines flights from Greenville to San Diego. The one-way connecting flight with American Airlines departs from Greenville-Spartanburg International Airport on Sun, Mar 16, arriving at San Diego International Airport. One-way Prices start from €213 including taxes and charges.

      • GSP07:04
        7h 7m
        1 stop
        SAN11:11
        Tue, Mar 18|Greenville - San Diego|United Airlines
        €217
        €217

        Choose United Airlines flights from Greenville to San Diego. The one-way connecting flight with United Airlines departs from Greenville-Spartanburg International Airport on Tue, Mar 18, arriving at San Diego International Airport. One-way Prices start from €217 including taxes and charges.

      • GSP05:30
        7h 1m
        1 stop
        SAN09:31
        Thu, Mar 6|Greenville - San Diego|American Airlines
        €218
        €218

        Choose American Airlines flights from Greenville to San Diego. The one-way connecting flight with American Airlines departs from Greenville-Spartanburg International Airport on Thu, Mar 6, arriving at San Diego International Airport. One-way Prices start from €218 including taxes and charges.

      • GSP01:00 pm
        3h 5m
        Nonstop
        SAN02:00 pm
        Sat, Feb 22|Greenville - San Diego|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Greenville to San Diego flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA5344

    American Airlines

    05:30

    GSP

    1.1h

    06:34

    CLT

    SMTWTFS
    Search

  2. AA1954

    American Airlines

    08:55

    CLT

    5.3h

    11:10

    SAN

    S--WT-S

  3. DL3028

    Delta Air Lines

    05:45

    GSP

    1.1h

    06:48

    ATL

    SMTWTF-
    Search

  4. DL725

    Delta Air Lines

    08:20

    ATL

    4.8h

    10:05

    SAN

    SMTWTFS

  5. UA4722

    United Airlines

    06:30

    GSP

    2.4h

    07:53

    ORD

    SMTWTFS
    Search

  6. UA660

    United Airlines

    09:06

    ORD

    4.6h

    11:43

    SAN

    SMTWTFS

  7. UA1394

    United Airlines

    07:00

    GSP

    2.8h

    08:46

    IAH

    SMTWTFS
    Search

  8. UA2491

    United Airlines

    09:31

    IAH

    3.5h

    11:03

    SAN

    SMTWTFS

  9. DL1273

    Delta Air Lines

    15:42

    GSP

    1.1h

    16:46

    ATL

    SMTWT-S
    Search

  10. DL712

    Delta Air Lines

    19:50

    ATL

    4.8h

    21:37

    SAN

    SMTWTFS

  11. AA2732

    American Airlines

    16:15

    GSP

    2.9h

    18:09

    DFW

    -MT--F-
    Search

  12. AA1243

    American Airlines

    19:54

    DFW

    3.3h

    21:13

    SAN

    SMTWTFS

  13. DL3095

    Delta Air Lines

    17:05

    GSP

    1.1h

    18:10

    ATL

    SMTWT-S
    Search

  14. DL731

    Delta Air Lines

    17:49

    ATL

    4.8h

    19:35

    SAN

    SMTWTFS

  15. DL4933

    Delta Air Lines

    17:25

    GSP

    1.8h

    19:15

    DTW

    SMTWT--
    Search

  16. DL700

    Delta Air Lines

    20:30

    DTW

    5.0h

    22:30

    SAN

    S-TWT-S

  17. AA3385

    American Airlines

    19:48

    GSP

    3.0h

    21:45

    DFW

    S--WTFS
    Search

  18. AA2568

    American Airlines

    22:39

    DFW

    3.1h

    23:44

    SAN

    SMTWT-S

  19. DL3007

    Delta Air Lines

    19:55

    GSP

    1.1h

    21:02

    ATL

    SMTWT-S
    Search

  20. DL896

    Delta Air Lines

    21:15

    ATL

    4.8h

    23:03

    SAN

    SMTWTFS
Find more flights and airlines

Find the best time to fly from Greenville to San Diego

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight tickets from Greenville (GSP) to San Diego (SAN) the cheapest?

    Airlines adjust prices for flights from Greenville to San Diego based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Greenville (GSP) to San Diego (SAN) cost?

    According to Trip.com's data, the lowest price is around €411.

  • What is the transportation method from the main airport to downtown in San Diego?

    • The distance from San Diego International Airport to downtown is about 3 km. It takes about 20 minutes by taxi.

How to find a cheap flight from Greenville to San Diego

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Greenville to San Diego. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Greenville to San Diego

Cheapest nonstop flight price€167
Off-season for travelMarch
Peak season for travelNovember
Flight distance3,208.42 km
Popular airlineDelta Air Lines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.